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This stress is often amplified by drought and high temperatures (Kumar 2020) and manifests as osmotic imbalance, ionic toxicity, and excessive reactive oxygen species (ROS) production, which disrupt redox homeostasis, cell division, membrane integrity, and cytoplasmic metabolism (Mushtaq et al

Interest in treatment for mild TBI is at an all time high due to its association with the development of chronic traumatic encephalopathy and other neurodegenerative diseases, yet therapeutic options remain limited

Severity of the injury, an indirect measure of the mechanical force sustained from a TBI, may also play a role in the development of CTE, with evidence of neuroinflammation in the brain 17 years after the initial injury (50)

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