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Furthermore, in a recent study from the United Kingdom, the calculated frequency of individuals predicted to carry two mutant pathogenic ATP7B alleles was ~1 per 7,000 individuals, with heterozygote mutations found in up to 2.5% of the general population 12

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[DOI] [PMC free article] [PubMed] [Google Scholar] 226.Gustavsson A., Norton N., Fast T., Frlich L., Georges J., Holzapfel D., Kirabali T., Krolak-Salmon P., Rossini P.M., Ferretti M.T., et al

Prisutan je u svakoj eliji i bitan je za eliminaciju slobodnih radikala

This occurs as a result of mistreatment of the protein alpha-synuclein and its aggregated forms and also as a result of the gradual loss of nigrostriatal neurons [46]