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In the rat model of neuropathic pain induced by CCI, Fer-1 upregulates GPX4 expression, downregulates ACSL4 expression, and decreases the content of iron in the spinal cord, while erastin has the opposite effect

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The treatment efficacy seemed to be similar for both genders and all ages, probably because nutritional requirements are similar for both genders and all ages (after normalizing for caloric intake)

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