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GSSSSG may, in principle, regenerate two GSSH molecules (net reaction: GSSSSG + 2 GSH GSSG + 2 GSSH)

WangLShiHLiuYZhangWDuanXLiMet al

The alveolar epithelium is primarily composed of type I AECs (AEC-I) and type II AECs (AEC-II)

Psychosocial stress Psychosocial factors such as chronic stress, depression, and social isolation exert bidirectional regulatory effects on physiological aging processes through the brainperipheral organ axis, becoming a critical upstream risk factor for cognitive frailty

Torres-Ramos YD et al
