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Standard protocols often recommend cycling to prevent receptor desensitization, while lower doses may allow for more extended use without the same concerns about diminishing returns

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[DOI] [PubMed] [Google Scholar] 75.Shepherd S., Gibson P

Vedolizumab is a humanised monoclonal antibody that inhibits lymphocyte adhesion, particularly the mucosal addressin cell adhesion molecule-1 (MAdCAM-1), which is selective for 47 integrin[86]