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[DOI] [PMC free article] [PubMed] [Google Scholar] Watson GE, Evans K, Thurston SW, van Wijngaarden E, Wallace JMW, McSorley EM, Bonham MP, Mulhern MS, McAfee AJ, Davidson PW, Shamlaye CF, Strain JJ, Love T, Zareba G, Myers GJ

Researchers found that BPC-157 treatment significantly accelerated healing through enhanced angiogenesis and collagen deposition

In clinical trials, doses are escalated gradually over several weeks to improve tolerability a process known as dose titration

doi: 10.1038/s41467-020-14729-8

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Other evidence shows in a murine breast cancer model (4T1) that following phagocytosis of cellular debris from tumor cells treated with chemotherapy (paclitaxel) TAMs upregulate the expression of HO-1, which in turn hinders M1 polarization and attenuates the response to chemotherapy