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Sirtuin 5 (SIRT5), which is overexpressed in lung cancer, decrease the succinylation of GLS to regulate ammonia production and ammonia-induced autophagy [67]

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doi: 10.1016/0921-8734(92)90030-s, 20 HarrisA

While no variants in/near these genes have been associated with hypertension in genome-wide association studies, it is possible that these are associated with salt-sensitive hypertension