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Gene set enrichment analysis (GSEA) was performed with 1000 permutations to identify enriched biological functions and activated pathways from the molecular signatures database (MSigDB), which included hallmark gene sets, positional gene sets, curated gene sets, motif gene sets, computational gene sets, GO gene sets, oncogenic gene sets, and immunologic gene sets

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If endogenous glutaredoxin availability or activity is limiting, then rxYFP may become oxidized by other processes (e.g., by ROS from the respiratory chain) and thus lose its ability to act as a specific reporter for the glutathione redox couple

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