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The inflammation results in elevated expression of IL-6 which then leads to inappropriate levels of hepcidin being produced by the liver

Holland D, Faltin Z, Perl A, Ben-Hayyim G, Eshdat Y (1994) A novel plant glutathione peroxidase-like protein provides tolerance to oxygen radicals generated by paraquat in Escherichia coli

The Ce6@PTP/DP micelle produces a large number of ROS under light, stimulates PDT, inhibits the proliferation of tumor cells, and triggers the release of PTX from prodrug PTP, thus improving its therapeutic effect (Table 3)

Further studies found that inhibiting Omi/HtrA2 not only protects neurons, but also alleviates the apoptosis of brain ECs and the decreased TJs protein induced by LPS (Wang et al., 2018

For permanent solutions, a combination of treatments may be recommended

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