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[1] [2] Testosterone, by contrast, is a well-established androgen hormone used therapeutically in the UK for conditions such as confirmed hypogonadism and, under specialist supervision, as part of gender-affirming hormone therapy (which is generally considered off-label use in the UK and requires specialist oversight)

M.MikiD.OchiH.NischalkeH.-D.BojungaJ.BibertS.et al

Arzate-Mejia RG, Mansuy IM

We supposed that the mutations of K240 and H241 influenced the apo-holo transition and led to weak PLP binding and the loss of decarboxylase activity

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Phase II liver detoxification involves a process called conjugation