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Anim Feed Sci Technol 173:111133 Lebda MA, Hashem AS, Taha NM, Mandour AE, Edres HA (2020) l-carnitine mitigates bisphenol A-induced hepatic toxicity via activation of Nrf2 and inhibition of pro-inflammatory cytokine gene expression in rats

The authors suggested that environmental factors, such as ambient temperature, may modulate hypothalamic-pituitary-thyroid axis activity, contributing to fluctuations in disease activity or laboratory values in patients with Hashimotos thyroiditis, highlighting the importance of considering the seasonal context in the diagnosis and treatment of thyroid disorders.Finally, living in overly sterile environments with limited exposure to environmental agents has been linked to a higher incidence of HT, possibly due to reduced immune system training and altered microbiota composition (Klubo-Gwiezdzinska And Wartofsky 2022)

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In another study, researchers used RNA sequencing to determine distinct gene regulation in the prefrontal cortex of treated pups [37]
