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Borbly AA, Daan S, Wirz-Justice A, Deboer T

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For example, the combined use of the DNA demethylating agent decitabine and vitamin C can synergistically enhance the activity of the TET family (particularly TET2 and TET3), reverse gene expression dysregulation caused by abnormal DNA methylation, and ameliorate hematopoietic abnormalities resulting from TET2 mutations

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