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et al.) (Springer, 2020)

In addition, CR3 lacks a secondary structure 58,59

If tolerance is good and no concerning reactions occur, consider increasing to twice-daily application or moving to a 1 percent concentration

doi: 10.3390/gels8010062

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We also lack the ordinary pharmacological basics a clinician would want before recommending anything: well-characterised human pharmacokinetics, dose-response and safety ceilings, interaction data with common medications, and any signal about effects in people with pre-existing cancer risk the population for whom a telomerase-activating compound is most theoretically concerning