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The authors acknowledge that their interpretation is limited by inadequate knowledge of the function of the ALA alleles of GPx-1 gene

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Brinkmann V, Reichard U, Goosmann C, Fauler B, Uhlemann Y, Weiss DS, et al

Pott J, Kabat AM, Maloy KJ

[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Zhang Z, Zhang L, Zhou L, Lei Y, Zhang Y, Huang C: Redox signaling and unfolded protein response coordinate cell fate decisions under ER stress

For instance, GKT137831 selectively inhibits NOX1 and NOX4, reducing ROS generation and fibrotic signaling in diabetic vasculature [457]