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(111) demonstrated that in Caco-2 epithelial cells, nitric oxide produced during exposure to Clostridium difficile toxin facilitated HIF-1 stabilization through iNOS-dependent S-nitrosylation

Cardiovascular Abnormalities in Sickle Cell Disease

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2014 Feb;13(1):8-12 Aquilano K, Baldelli S, Ciriolo MR

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In post-surgical or critically ill patients, glutamine may improve nitrogen balance, preserve intestinal integrity, maintain intracellular glutamine levels, and reduce hospital stay (3) (4) (12) (13) (40) , but data on whether it can prevent infections (5) (40) or improve clinical outcomes (57) are mixed and it did not reduce the time to discharge alive from hospital in patients with severe burns (52)