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In spite of the low percentage of opioids consumption compared to other illegal drugs (0.1 %) ( ENCODAT, 2017 ), an ascendant trend is observed, which could be increased in the next few years, due to a series of factors, such as a higher demographical movement between USA and Mexico, the increase of diseases requiring a more effective pain management, the inclusion of opioids in health systems and insurances, the change in laws regarding the medical use of opioids and the illegal production of synthetic opioids ( WHO, 2017

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the ability to obtain, maintain, and enforce any patents or other intellectual property rights in respect of the Companys product formulations and delivery technologies