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Front Cell Neurosci 11:332

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In bone defect models, including segmental defects in rabbits, the enhanced osteogenic effects, improved callus formation, and better healing compared with bone marrow control and autologous graft control were observed

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Documented side effects are usually mild to moderate: Injection-site pain, redness, or bruising Flushing Increased heart rate Nausea or gastrointestinal upset Headache Urinary changes or a fishy body odor at higher choline doses Because these are compounded products, sterile technique, pharmacy sourcing, and formulation verification matter