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Zorn, J

In GPX4 brain-inducible knockout mouse models, vitamin E deficiency accelerated hippocampal neuronal degeneration and behavioral decline (Wortmann et al., 2013)
In the palmitic acid (PA)-induced ceramide synthase 6 (CERS6)-deficient HK-2 and CERS6 knockdown db/db mouse models, aggravation of DKD symptoms and renal interstitial fibrosis were found, possibly due to the interaction of CERS6-derived ceramide with PINK1 to inhibit PINK1/Parkin-mediated mitophagy, which aggravates DKD [118]
"PTSD and complex PTSD, current treatments and debates: a review of reviews"
Intracerebral injection of CpG oligonucleotide for patients with de novo glioblastoma-A phase II multicentric, randomised study
Additionally, H3K18 lactylation has been implicated in promoting arsenic-associated idiopathic pulmonary fibrosis progression via the YTHDF-1/N6-methyladenosine (m6A)/NREP pathway [115]
