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10.1002/ejlt.201400329

Pathogenesis: The nevus occurs from nevus cells in the epithelium, the basement membrane, connective tissue, or in combination from these sites

Research uses MT-1 to study whether the anti-inflammatory and melanogenic arms of MC1R biology can be pharmacologically dissected through downstream pathway selective interventions examining whether PKA inhibition differentially affects the two outputs and contributing to understanding of how MC1R-cAMP signalling branches to produce distinct cellular outcomes simultaneously