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Proc Natl Acad Sci U S A 104:1389-1394

70 JeltschA.JurkowskaR

doi: 10.1038/s41401-023-01062-1 [DOI] [PMC free article] [PubMed] [Google Scholar] 196.Yuan Z, Zhao J, Wang Z, et al

21 Interestingly, ASH can be transmitted from patients to healthy germ-free and conventional mice via intestinal microbiota transplantation

The most well-established mechanisms include through (1) NF-B inhibition, (2) suppression of STING signaling, (3) interference of pro-inflammatory cytokine transcription, and (4) through NRF2 target gene signaling pathways

This lower nicotine level is a limitation of this study, especially as the nicotine levels of currently used e-cigarette disposables on the market are 50 mg/mL