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Description
Sixteen percent

They deliver a high dose of B12 directly into the muscle (intramuscularly) or under the skin (subcutaneously)

doi:10.1177/23743735231151767

The technique is learnable, but the decisions around it (do you actually need it, what dose, how often, and is something else being missed) are medical judgements, and getting them wrong carries real cost

Implications Resistance mechanisms that undermine the immunomodulatory effects of CD38targeting therapies can be tumor intrinsic, such as the downregulation of CD38 surface expression and expression of complement inhibitor proteins, and immune microenvironmentrelated, such as changes to the natural killer (NK) cell numbers and function in the bone marrow niche
If the goal is scale weight, this is not the right tool
