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Toxicology 2006

There were no significant cognitive effects in male TDP-43 K408R/K408R mice, however mild impairments were observed on the rotarod test at 9 months of age (2-way ANOVA p = 0.0273, Table S2)

Abstract Globally, more than 10 million people developed active tuberculosis (TB), with 1.4 million deaths in 2020

Histone deacetylase (HDAC) inhibitors Recent evidence indicates that HIF-1 acetylation by p300/CBP associated factor (PCAF) at K 674 in an environment of low NAD + is critical for promoting p300 recruitment and subsequent expression of HIF-1 target genes

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In mice, low concentrations of zinc stimulate ceramide formation, leading to DC apoptosis through a mechanism involving acid sphingomyelinase