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Similarly, 2-acetylacteoside enhanced the expression of phosphorylated Akt in cultured NSCs after oxygenglucose deprivation/reoxygenation, promoting neurogenesis (Wang et al., 2024)

however, patients with T2DM are at an increased risk of reactivation of LTBI due to increased risk of granuloma failure ( mycobacterium dissemination and active infection 5

Intrinsic immunity has evolved with the body over tens of thousands of years and has a well-established and elaborated system, and the skillful activation of some beneficial immune capacity can be pivotal and essential in combating biofilms ( in situ immunity via advanced biomimetic nanomaterials that act as vaccines to produce a powerful and sustained antimicrobial effect with self-immune cells, such as neutrophils, macrophages, and DCs (Kimkes and Heinemann, 2020)