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These factors contribute to mitochondrial dysfunction and cognitive impairment in affected individuals ( 5.3 Manifestations of neuropsychiatric system injury Ketamine abuse commonly manifests as dissociative symptoms, such as altered consciousness, detachment from the environment, and sensory loss ( 5.4 Auxiliary examination Neuroimaging studies have provided critical insights into ketamine-induced neurotoxicity

Logsdon AF, Rhea EM, Reed M, Banks WA, Erickson MA (2021) The neurovascular extracellular matrix in health and disease

Bajic, V

It catalyzes the conversion of free long-chain fatty acids into acyl-CoA derivatives, facilitating their integration into cell membranes ( 2.1.4 Iron-responsive element-binding protein 2 Other molecules involved in lipid and iron metabolism also regulate ferroptosis, including iron-responsive element-binding protein 2 (IRP2) ( 2.2 Organelle-specific regulation of ferroptosis Organelle interactions are fundamental to the regulation of ferroptosis and include various cellular compartments such as mitochondria and the endoplasmic reticulum (ER), which work in conjunction with lipid metabolic pathways ( Figure 2 )

Drug-microbiota interactions: an emerging priority for precision medicine

The number of times that the motif C-X-X-C appears in human genes are near 19,000 in about 6,000 proteins (www.uniprot.org), but note that not all of these motifs will appear in native proteins, and not all proteins having the motif C-X-X-C will be an oxidoreductase (Table 5)