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Use in populations with active malignancy requires caution in principle because proangiogenic agents can theoretically influence tumor vascularization

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[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Wang-Sattler R., Yu Z., Herder C., Messias A.C., Floegel A., He Y., Heim K., Campillos M., Holzapfel C., Thorand B., et al

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Data suggest that the primary heat shock transcription factor HSF-1 is not essential for celastrol-mediated protection