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RTD is among the most riboflavin-responsive genetic neurological disorders, with early diagnosis and high-dose supplementation (1050 mg/kg/day) capable of reversing neurological deficits ( Downstream, RFK (riboflavin kinase) is essential for converting riboflavin to FMN

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Another study in *Life Sciences* demonstrated significant improvement in inflammatory bowel disease markers within four weeks of treatment (Vukojevic et al., 2018)

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Specifically, commenters were concerned about providers' inability to influence results based on factors outside of their control, including COVID-19 vaccine hesitancy

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