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CSE is activated by phosphorylation by AKT and expression is upregulated by farnesoid X receptor (FXR) and specificity protein 1 (Sp1) [39]
10.1111/j.1365-2982.2010.01664.x 94 CuiL.LiS.WangS.WuX.LiuY.YuW.et al
However, many people with fatty liver have other risk factorssuch as metformin use, proton pump inhibitors, or dietary restrictionsthat can independently lead to B12 deficiency, making monitoring important when symptoms or risk factors are present
