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Although formal tests for normality (ShapiroWilk and DAgostinoPearson tests) indicated deviations from perfect normality, the distributions were manually inspected and found to be sufficiently close to normality to justify the use of the limma approach

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These inhibitors exhibit pharmacokinetic and metabolic stability, suitable for in vivo studies, and have been shown to effectively block the FSP1-mediated cellular defense mechanism against ferroptosis

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