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Clinical significance of this inhibition is demonstrated by the fact that inhibition of CYP3A4 by metformin results in reduced mitochondrial respiration leading to reductions in cancer cell growth

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Specifically, under normal conditions, the eukaryotic initiation factor-2 (eIF2) complex (composed of alpha, beta, and gamma subunits) assists with RNA translation via ribosomal recognition of the AUG start codon [227]

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discard if discolored or contains precipitates