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Symptoms of glutathione synthetase deficiency may include: Seizures Hampered reaction to speech and physical stimuli Poor coordination Intellectual disability Vulnerability to bacterial infections Low glutathione levels are also associated with a large number of disorders, including some types of cancer and AIDS

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Vitamin B12 is an essential nutrient that is important for the health of the nervous system, the production of red blood cells, and the functioning of many other processes in the body

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However, as mentioned before these antioxidants have a very short half-life and are only effective after mild bouts of oxidative stress

So the benefit is real, but it is indirect and it depends on whether you were low to begin with