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Compounding pharmacies create these formulations under Section 503A or 503B of the Federal Food, Drug, and Cosmetic Act

Remarkable differences in nuclear factor kappa-B (NF-B) activity, cytokine production, leukocyte migration that involved in the inflammatory response, and other biological targets (such as NCOA4, glutamate-cysteine ligase catalytic subunit and Aldo-keto reductase family 1-member C1) are also observed when compared to those in controls

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doi: 10.1085/jgp.201611581 8 BailesH

Because the polymer can absorb H + ions, it shows weak buffer properties, which are critical to its use as a DNA delivery agent