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Vitamin B12 plays a role in collagen synthesis, which can help improve skin texture and reduce the appearance of fine lines and wrinkles

Evidence type: Human RCT | Observational | Animal | In vitro | Regulatory Mechanism of Action 5-Amino-1MQ works by blocking the NNMT enzyme , which is responsible for consuming nicotinamide and depleting NAD+ stores

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Vitamin B12 is a water-soluble vitamin, meaning that your body excretes what you dont need in your urine, including any excess consumed via supplements or food

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Meanwhile, 5-Amino-1MQ helps inhibit an enzyme called NNMT, which normally diverts NAD+ precursors away from energy production pathways