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(31), where higher L-carnitine concentrations in the medium inhibited -butyrobetaine hydroxylase activity but left -N-trimethyllysine hydroxylase activity unaffected

However, skeletal muscle-specific carnitine palmitoyltransferase 2 (CPT2)-deficient mice accumulate large amounts of acylcarnitine in muscle and plasma and still preserve insulin sensitivity [75], highlighting the role of acylcarnitine only as an indicator of FAO rather than as a direct mediator of insulin resistance [76]

This bodys own substance can be found mainly in the musculature and in the heart muscle

M., Yang, M

(2011) Relationship between the pattern of hepatic iron deposition and histological severity in nonalcoholic fatty liver disease

Park SO, Kim WK