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dissertation, Georgetown University College of Arts & Sciences, Washington, DC

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4 Mitochondrial DNA: a key player and victim in HIV pathogenesis Mitochondrial DNA (mtDNA) occupies a dual role in HIV pathogenesis: it is both a target for viral-induced damage and a potent activator of innate immune pathways that drive chronic inflammation

Glutathione is a tripeptide (glutamate-cysteine-glycine) that maintains cellular redox balance and detoxification

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Med Clin North Am 2008