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Off-target and pathway specificity checks: Designing experiments to differentiate ERR-driven effects from estrogen receptormediated pathways, since ERRs are distinct targets that require careful assay controls

TUVP is typically performed on an outpatient basis, and most patients are able to go home the same day without the need for a catheter

However, the predominance of in vitro and acute in vivo models highlights the need for systematic evaluation of long-term safety, biodistribution, and translational relevance in clinically relevant neurological settings [151153]

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After care kit is included