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Development of Nanozyme Based Sensors as Diagnostic Tools in Clinic Applications: A Review. Journal of Materials Chemistry B 11: 67626781

4 AidaR.YoshidaT.IchimuraK.GotoR.ShibataM

If GSH and GSSG were separated by isocratic elution where the ratio of TFA and methanol was 99:1 (v/v), it would be the most sensitive, but the retention times of the separated substances would be too high

And it took an average of 10 months (612) before full competitive activity

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Besides the acute phase gastrointestinal effects which may lead to up to 10% of people discontinuing the drugs, there are other potential GI side effects of obstruction, excessive loss of muscle mass, and potentially association with some eye disease adverse events
