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Ethnicity imposes greater risk for development of neuropathy following vincristine, which is metabolized via the cytochrome P450 (CYP) 3A4 and CYP3A5 pathways (Dennison et al., 2007)

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Vegetables and fruits are good sources of carotenoids as well, but the carotenoids that are known to possess antioxidant activities are -carotene, -carotene, lycopene, and lutein (Fig