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Cancer Discov 2014;4:41522

10.1016/S1470-2045(10)70294-1 355 WefelJ

Since an overexpression of the protein MCL-1 has been related with drug resistance [419], a depletion of MCL-1 by everolimus can suppress the homologous recombination repair in GBM, increasing DNA damage [420]

However, it has been proposed that activation of this common pathway through physiological signals results in term labor, while preterm labor might occur from spontaneous activation of isolated aspects of the common pathway by the presence of pathological conditions that may be induced by multiple causes [238] or risk factors

Constitutive exposure of phosphatidylserine on viable cells

Targeting the mevalonate pathway suppresses VHL-deficient CC-RCC through an HIF-dependent mechanism