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If overdose is suspected or if neurologic symptoms emerge, stop further dosing and seek medical evaluation

Patients taking warfarin, heparin, DOACs (direct oral anticoagulants), or high-dose aspirin should discuss potential interactions with their provider before starting BPC-157

In addition to oxidative stress, excessive copper ion accumulation alters energy metabolism patterns within cardiomyocytes by inducing abnormal aggregation of thioctylated proteins and loss of iron-sulfur cluster proteins in the respiratory chain complex through direct binding to thioctylated proteins in the mitochondrial TCA cycle (76)

Obesity-dependent adipokine chemerin suppresses fatty acid oxidation to confer ferroptosis resistance