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It can also affect thyroid hormone medications, reducing their effectiveness

It is generally safe, but taking it with a small snack can help if you have a sensitive stomach
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Hum Reprod update
Microbial enzymes and biotechnology

Although nhr-49 is not involved in ARD when beginning the starvation period during the mid-L3 stage (Gerisch et al., 2020), starvation onset in mid-L4 worms requires nhr-49 for entry into and recovery from adult reproductive diapause (Eustice et al., 2022)