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[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Moris D., Spartalis M., Spartalis E., Karachaliou G.-S., Karaolanis G.I., Tsourouflis G., Tsilimigras D.I., Tzatzaki E., Theocharis S

By reducing IGFBP binding to negligible levels while preserving IGF1R affinity, LR3 enables sustained IGF1R activation in cell culture and in vivo models with practical dosing protocols
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Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work

KPV stands for lysine-proline-valine
And so I'm not saying that it reverses aging, but in these studies, it appears to have extreme mitochondrial benefits, which would logic to reason as to why we're seeing such phenomenal results with these treatments