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Drug Metabolism and Disposition, 45(12), 1266-1275

Therefore, a dose-response relationship could not be evaluated, and the events cell proliferation and hyperplasia are not supported by available data

Cell-to-cell transmission of polyglutamine aggregates in C

Neutrophil elastase in the development of nephrogenic systemic fibrosis (NSF)-like skin lesion in renal failure mouse model

The data, together with the data from the same study measuring pyruvate levels described above, indicate that fasting increased the fumarate/pyruvate, and so also likely increased the malate/pyruvate, indicative of the [NADPH]/[NADP + ], in the spinal cord and several brain regions, including the hippocampus, brainstem, olfactory bulb, and potentially to a smaller extent in the cortex, while potentially decreasing in the hypothalamus (Shao et al., 2023)