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Indeed, such abnormal presence of mitochondria in circulating red blood cells causes increased oxygen consumption, ROS generation, and hemolysis in SCD patients 50,51
Rahaman MM, Hossain R, Herrera-Bravo J, et al
Science 278 , 369 (2022)
Beer SM, Taylor ER, Brown SE, Dahm CC, Costa NJ, Runswick MJ, Murphy MP
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Wissenschaftliche Referenzen Seiwerth et al
