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The increased level of inflammatory cytokines is perhaps a result of dysbiosis of the gut microbiota, which may further weaken the integrity of the gut barrier

PMID: Summary Keywords autoimmune diseases, butyrate, clostridium, immune interaction, immunotherapy Citation Zhan J-Y, Wang W-R, Zhan T, Yang J-Y, Liang Y, Yu R-H and Wang X-H (2026) Recent advances in the positive role of Clostridium in autoimmune diseases: as a crucial regulator of restoring immune-metabolic equilibrium

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Protective effects of BPC 157 on liver, kidney, and lung distant organ damage in rats with experimental lower-extremity ischemiareperfusion injury Summary: This study on rats investigated the protective effects of BPC 157 against remote organ damage (liver, kidneys, and lungs) following a lower extremity ischemia-reperfusion injury

Given that it is in early stages of development and the lack of clinical data, 5-amino-1MQ's safety and efficacy remain to be thoroughly investigated through comprehensive clinical trials