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[] In the rat brain, this preventive therapy decreased myeloperoxidase activity, lipid peroxidation, protein carbonylation and nitrite/nitrate concentrations brought on by initial and late-life stress

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Compliance with ethical standards Conflict of interest On behalf of all authors, the corresponding author states that there is no conflict of interest

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In vivo efficacy studies IACS-010759 and palbociclib were purchased from MedchemExpress and were administered orally 5 days per week at a dose of 10 and 75 mg/kg, respectively