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Concurrently, it activates the HOXA9/MENIN pathway to upregulate the expression of key enzymes in the serine synthesis pathway and boost endogenous serine production, thereby remodeling serine metabolism and driving leukemogenesis (96)

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An NF kappa B-like factor is essential but not sufficient for cytokine induction of endothelial leukocyte adhesion molecule 1 (ELAM-1) gene transcription Nucleic Acids Res 1991 19 : 26452653 Iademarco MF, McQuillan JJ, Rosen GD, Dean DC