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Metabolic modulation via mTOR pathway and anti-angiogenesis remodels tumor microenvironment using PD-L1-targeting codelivery

(2019) 73:35463.e3

Heterogeneity is seen both in terms of the number of basepair mismatches within the textbook 2 hexamer-containing ARE sequence, the number of hexamers per ARE, and the make-up of the spacing between the individual hexamers in AREs

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This may be useful as a model for increasing resilience to stressors in at-risk populations. The above study shows that LAC enhances resilience to stress

& Hussain, I
