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1 Introduction Osteoarthritis (OA) is a prevalent, progressive, multifactorial joint disease characterized by chronic pain and dysfunction (James et al., 2018)

Therefore, the need for innovative therapeutic approaches is urgent, and in recent years, targeted or chemotherapeutic drug delivery approaches using nanoparticles have started to emerge

International Journal of Hygiene and Environmental Health , 248 , 114091

Activation of the MET receptor regulates synapse formation [47] [48] [49] [50] [51] and can impact the development and function of circuits involved in social and emotional behavior

10.1016/j.phrs.2020.105119 14 DimitroulisD.DamaskosC.ValsamiS.DavakisS.GarmpisN.SpartalisE.et al (2017)

Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways