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*Correspondence: Liping Qu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Acknowledgements Research reported in this publication was supported by the National Institute of Neurological Disorders and Stroke of the National Institutes of Health under Award Number RF1NS135548, National Institute on Aging of the National Institutes of Health under Award Numbers R01AG082207, R01AG083947 and R01AG081874, and by the American Heart Association Career Development Award 24CDA1269588