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Effect of zinc supplementation on antioxidant defenses and oxidative stress markers in patients undergoing chemotherapy for colorectal cancer: a placebo-controlled, prospective randomized trial

Vitamin B6 Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6

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Nguyen TH, Nagasaka R, Ohshim T (2013) The Natural Antioxidant Ergothioneine: Resources, Chemical Characterization, and Applications

NAC is a key precursor to glutathione and is used clinically to support liver detoxification

However, in DMT1-mutant models, this recycling pathway is disrupted, leading to iron sequestration in lysosomes in a redox-inactive form, thereby lowering cytosolic Fe 2+ levels and suppressing Fenton reactiondriven oxidative stress and ferroptosis